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Medical Chemistry: textbook / V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

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Авторы: В.Ю. Цубер, А.А. Котвицкая, К.В. Тихонович; под редакцией В.Ю. Цубер
Гриф: рекомендовано ученым советом Полтавского государственного медицинского университета
Аудитория: для студентов медицинских учреждений высшего образования, обучающихся на английском языке
Издательство: Всеукраинское специализированное издательство «Медицина»
Язык: английский
Год: 2022
Количество страниц: 392 (черно-белые)
ISBN: 978-617-505-895-4
Всеукраинское специализированное
издательство «Медицина»

Описание книги Medical Chemistry: textbook / V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

The textbook outlines theoretical foundations of bioenergetics and kinetics of biochemical reactions, fundamental principles of chemical equilibrium; chemical properties and biological role of biogenic elements; structure of coordination complexes. Considerable attention is given to the theory of solutions and dissolution processes, as well as to importance of pH values for assessment of the acid-base state of blood and other biological fluids. Mechanisms of electrode potentials, surface phenomena, and their role in life of the organism are described. The textbook also describes classification and fundamental properties of dispersed systems and colloidal solutions; theoretical foundations of properties of macromolecular compounds, and their role in living organisms.
The textbook is intended for use by students of higher medical educational institutions studying in English.

Содержание книги Medical Chemistry: textbook / V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

Preface
Chapter 1. Chemical thermodynamics
Thermodynamic system
Thermodynamic parameters and thermodynamic processes
Internal energy
Enthalpy
Standard enthalpy change
The Hess’ law
Calorimetry
Energy values of nutrients
The First Law of Thermodynamics 
Entropy
Second Law of Thermodynamics 
Free energy
Spontaneous processes
Macroergic compounds in the organism
Chapter 2. Chemical kinetics
Rate of chemical reaction
Factors that affect reaction rate
Effect of concentrations of substances on reaction rate.
Law of mass action
Molecularity of reactions
Reaction order
Effect of temperature on reaction rate
Recap of collision theory of reaction rate
Complex reactions
Catalysis
Properties of catalysts
Important concepts of catalysis
Catalysis by phase: heterogeneous and homogeneous catalysts
Catalysis by chemical interaction: acid-base and redox catalysts
Mechanism of catalysis
Theories of catalysis
Enzymes
Properties of enzymes
Measuring enzyme activity
Classification of enzymes
Properties of the active site
Kinetics and mechanism of enzyme activity
Factors affecting velocity of enzymic reactions
Inhibition of enzyme activity
Regulation of enzyme activity
Medical enzymology
Chapter 3. Chemical equilibrium. Heterogeneous equilibriums in the organism
Chemical equilibrium
Kinetics of chemical equilibrium
Factors affecting chemical equilibrium. Le Chatelier’s principle
Thermodynamics of chemical equilibrium
Solubility product. Heterogeneous equilibriums in the organism
Solubility product
Heterogeneous equilibriums in the organism
Formation and remodeling of bone tissue
Formation of kidney stones
Chapter 4. Biogenic elements
Classification of biogenic elements by the amount in the organism
Classification of biogenic elements by the electron structure of the valence shell
Macroelements
Macroelements of the s-block
Macroelements of the p-block
Microelements
Microelements of the s-block
Microelements of the p-block
Microelements of the d-block
Сhapter 5. Coordination complexes
Structure of coordination complexes
Coordination number and denticity of ligands
Donor-acceptor mechanism of bond formation
Isomerism of coordination complexes
Classification of coordination complexes
Nomenclature of coordination complexes
Stability constant of coordination complexes
Chelate complexes
Coordination complexes in the organism
Chapter 6. Solutions. Solubility. Composition of solutions
Solutions
Classification of solutions
Solubility
Polarity
Mechanism of dissolution
Solubility of gases in liquids
Transport of gases in blood
Nernst distribution law
Composition of solutions
Mass fraction
Mole fraction
Molarity
Normality
Molality
Measurements of concentration of solutions. Titrimetric analysis
Methods of titrimetric analysis by chemical reaction
Acid-base titration
Complexonometric titration
Redox titration
Precipitation titration
Methods of titrimetric analysis by technique
Colligative properties of solutions
Vapor pressure depression
Equilibrium vapor pressure
Raoult’s Law
Boiling point elevation
Freezing point depression
Osmosis
Osmotic pressure
Osmolarity and osmolality
Isotonic, hypotonic, and hypertonic solutions
Plasmolysis and hemolysis
Solutions isotonic to blood
The osmotic pressure of blood. Osmoregulation
Chapter 7. Acids and bases. Buffer solutions
Electrolytes
Acids and bases
Ion theory (Arrhenius definition)
Proton theory (Brønsted-Lowry definition)
Electron theory (Lewis)
Dissociation of water
pH
Salt hydrolysis
Hydrolysis constant
Degree of salt hydrolysis
Buffer solutions
Types of buffer solutions
Mechanism of buffering
Buffer capacity
pH of buffer solutions. Henderson—Hasselbalch equation
Acid-base homeostasis
Buffer systems of blood
Disorders of acid-base homeostasis
Chapter 8. Electrode processes
Electrode potential
Galvanic cell. Electromotive force
Potentiometry
Diffusion potential
Membrane potential
Redox systems. Redox potentials
Redox reactions in the organism. Biological oxidation
Chapter 9. Surface phenomena. Adsorption. Chromatography
Surface phenomena
Adsorption
Surface phenomena at liquid-gas phase interfaces.
Surface tension
Surface-active compounds
Surface phenomena at liquid-liquid phase interface.
Emulsions
Surface phenomena at immobile phase interfaces
Molecular adsorption
Chromatography
Methods of chromatography by aggregate state of phases
Methods of chromatography by type of interaction
Methods of chromatography by technique
Chapter 10. Disperse systems. Colloidal solutions
Disperse systems
Colloidal solutions
Purification of colloidal solutions
Preparation of colloidal solutions
Structure of colloidal particles
Molecular-kinetic properties of colloidal solutions
Electrokinetic properties of colloidal solutions
Optical properties of colloidal solutions
Stability of colloidal solutions
Coagulation of lyophobic colloidal solutions
Flocculation
Colloidal protection
Chapter 11. High-molecular compounds and their solutions
Classification of polymers
Synthesis of polymers
Biopolymers
Proteins
Polysaccharides
Nucleic acids
Isoelectric point (pI) of proteins
Properties of polymer solutions
Viscosity of polymer solutions
Dissolution of polymers. Swelling
Gels
Index words

Авторы книги Medical Chemistry: textbook / V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

Характеристики книги Medical Chemistry: textbook / V.Y. Tsuber, A.A. Kotvytska, K.V. Tykhonovych

Издательство: Всеукраинское специализированное издательство «Медицина»
Форма: печатная книга (издание)
Вид: учебник
Язык: английский
Год: 2022
Количество страниц: 392 (черно-белые)
Обложка: твердая
Формат: 60х90/16
Вес: 527 г
ISBN: 978-617-505-895-4 (9786175058954)

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